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The correct answer is e. Steroid response is controlled by three different variables - the ability of the steroid to bind to the receptor, the ability of the receptor to bind to the DNA, and the ability of the receptor to bind to the target cell, or transcription factor in order for the gene to be translated. Even though MR, AR, PR, and GR all bind to the same receptor, it does not mean the conditions for steroid response are fully satisfied. In fact, only GR can bind to GRE and produce the desired effects (anti inflammatory response in body) due to the other two factors.
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